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The hypophyseal portal system connects


A) the anterior pituitary (adenohypophysis) with the hypothalamus.
B) the posterior pituitary (neurohypophysis) with the hypothalamus.
C) the anterior pituitary with the posterior pituitary.
D) the hypothalamus with its target organs.
E) the pituitary with its target organs.

F) A) and D)
G) B) and D)

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This figure shows the hypothalamo-pituitary-target organ relationships.Which hormone stimulates glucocorticoid secretion?


A) 1
B) 6
C) 8
D) 5
E) 10

F) C) and D)
G) A) and D)

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The zona fasciculata in the adrenal gland secretes


A) glucagon.
B) androgens.
C) estradiol.
D) aldosterone.
E) cortisol.

F) C) and D)
G) B) and D)

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The secrete(s) a hormone as a response to hypocalcemia.


A) thymus
B) thyroid gland
C) parathyroid glands
D) pineal gland
E) pituitary gland

F) A) and D)
G) A) and E)

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Addison disease is a consequence of a tumor of the adrenal medulla.

A) True
B) False

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Target organs most often regulate the pituitary gland via


A) negative feedback inhibition.
B) positive feedback inhibition.
C) up-regulation.
D) down-regulation.
E) antagonistic regulation.

F) C) and D)
G) A) and B)

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is not a steroid hormone.


A) Insulin
B) Cortisol
C) Progesterone
D) Aldosterone
E) Estradiol

F) C) and D)
G) C) and E)

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Absence of iodine in the diet leads to


A) hypoparathyroidism.
B) hypothyroidism.
C) hypocalcemia.
D) hypoglycemia.
E) hypoxemia.

F) A) and E)
G) D) and E)

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Diabetes insipidus is caused by


A) epinephrine hypersecretion.
B) cortisol hypersecretion.
C) aldosterone hypersecretion.
D) antidiuretic hormone (ADH) hyposecretion.
E) antidiuretic hormone (ADH) hypersecretion.

F) C) and E)
G) A) and C)

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The nervous system reacts to stimuli compared to the endocrine system, adapts compared to the endocrine system, and has effects compared to the endocrine system.


A) slowly; slowly; widespread
B) quickly; slowly; specific
C) quickly; quickly; widespread
D) quickly; quickly; specific
E) slowly; quickly; specific

F) C) and E)
G) A) and E)

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This hormone plays an important role in synchronizing physiological function with the cycle of daylight and darkness.


A) calcitonin
B) melanin
C) melatonin
D) hepcidin
E) inhibin

F) A) and E)
G) B) and D)

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The secretes several hormones that stimulate the development of lymphatic organs and regulates development and activity of T cells (white blood cells) .


A) thyroid
B) thymus
C) adrenal gland
D) spleen
E) parathyroid

F) C) and D)
G) All of the above

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Negative feedback inhibition occurs when


A) thyrotropin-releasing hormone (TRH) targets the anterior pituitary.
B) thyrotropin-releasing hormone (TRH) causes the anterior pituitary to release thyroid-stimulating hormone (TSH) .
C) thyrotropin-releasing hormone (TRH) targets the thyroid gland.
D) thyroid-stimulating hormone (TSH) targets the thyroid gland.
E) thyroid hormone (TH) targets the anterior pituitary.

F) A) and E)
G) B) and C)

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Hormones are normally secreted via ducts into the bloodstream.

A) True
B) False

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The neurohypophysis (posterior pituitary) secretes


A) prolactin (PRL) .
B) adrenocorticotropic hormone (ACTH) .
C) oxytocin (OT) .
D) thyroid hormone (TH) .
E) growth hormone (GH) .

F) B) and E)
G) A) and E)

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Thyroid hormone has a calorigenic effect.

A) True
B) False

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Eicosanoids are derived from


A) arachidonic acid.
B) leukotriene.
C) prostacyclin.
D) prostaglandins.
E) thromboxanes.

F) A) and B)
G) A) and C)

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This is the last step in the sequence of events happening when cyclic AMP acts as a second messenger.


A) G protein activates adenylate cyclase
B) cAMP activates protein kinases
C) adenylate cyclase produces cAMP
D) G protein is activated by the binding of a hormone to the receptor
E) enzymes are activated or deactivated by the action of protein kinases

F) B) and D)
G) A) and D)

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Eicosanoids are derived from steroids.

A) True
B) False

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Diabetes mellitus is characterized by the following except


A) hypoglycemia.
B) polyuria.
C) polyphagia.
D) polydipsia.
E) glycosuria.

F) None of the above
G) A) and E)

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