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In a Hardy-Weinberg population with two alleles,A and a,that are in equilibrium,the frequency of the allele a is 0.3.What is the percentage of the population that is homozygous for this allele?


A) 0) 09
B) 0) 49
C) 0) 9
D) 9) 0
E) 49.0

F) C) and D)
G) A) and B)

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Phenotypic characters,such as height in humans and coat color in horses are


A) influenced by multiple genes.
B) determined by a single gene locus.
C) a result of different chromosomes producing distinct phenotypes.
D) due to the presence of different alleles, which express the dominant color.
E) due to the blending of several genes.

F) C) and D)
G) None of the above

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Which of the following is a true statement concerning genetic variation?


A) It is created by the direct action of natural selection.
B) It arises in response to changes in the environment.
C) It must be present in a population before natural selection can act upon the population.
D) It tends to be reduced by the processes involved when diploid organisms produce gametes.
E) A population that has a higher average heterozygosity has less genetic variation than one with a lower average heterozygosity.

F) A) and B)
G) B) and E)

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The following questions refer to the following paragraph. HIV's genome of RNA includes the code for reverse transcriptase (RT) ,an enzyme that acts early in infection to synthesize a DNA genome from an RNA template.The HIV genome also codes for protease (PR) ,an enzyme that acts later in infection by cutting long viral polyproteins into smaller,functional proteins.Both RT and PR represent potential targets for antiretroviral drugs.Drugs called nucleoside analogues (NA) act against RT,whereas drugs called protease inhibitors (PI) act against PR. -Every HIV particle contains two RNA molecules.If two genes from one RNA molecule become detached and then,as a unit,get attached to one end of the other RNA molecule within a single HIV particle,which of these is true?


A) There are now fewer genes within the viral particle.
B) There are now more genes within the viral particle.
C) A point substitution mutation has occurred in the retroviral genome.
D) The retroviral equivalent of crossing over has occurred, no doubt resulting in a heightened positive effect.
E) One of the RNA molecules has experienced gene duplication as the result of translocation.

F) B) and E)
G) A) and B)

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In Kluane National Park,red squirrels have been recorded giving birth 18 days earlier than a decade ago.Offspring born earlier become larger and more likely to survive.What mode of selection best describes these current research findings?


A) stabilizing selection
B) directional selection
C) disruptive selection
D) transitional selection
E) Selection will vary depending on temperature and amount of snow in spring.

F) A) and B)
G) A) and C)

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Heterozygote advantage should be most closely linked to which of the following?


A) sexual selection
B) stabilizing selection
C) random selection
D) directional selection
E) disruptive selection

F) B) and E)
G) C) and D)

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Natural selection changes allele frequencies because some ________ survive and reproduce more successfully than others.


A) alleles
B) loci
C) gene pools
D) species
E) individuals

F) None of the above
G) B) and C)

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If the nucleotide variability of a locus equals 0%,what is the gene variability and number of alleles at that locus?


A) gene variability = 0%; number of alleles = 0
B) gene variability = 0%; number of alleles = 1
C) gene variability = 0%; number of alleles = 2
D) gene variability > 0%; number of alleles = 2
E) Without more information, gene variability and number of alleles cannot be determined.

F) None of the above
G) B) and D)

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Which of the following statements is a misconception about evolution of populations?


A) Natural selection acts on individuals.
B) Without genetic variation, evolution would not be possible.
C) Microevolution is a change in the genetic structure of a population over time.
D) For a population to evolve, individual members of the population must also evolve.
E) Most heritable variation involves quantitative characters.

F) All of the above
G) None of the above

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Sexual dimorphism is most often a result of


A) pansexual selection.
B) stabilizing selection.
C) intrasexual selection.
D) intersexual selection.
E) artificial selection.

F) All of the above
G) A) and C)

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Use this information to answer the following questions. You are studying three populations of birds.Population A has ten birds,of which one is brown (a recessive trait) and nine are red.Population B has 100 birds,of which ten are brown.Population C has 30 birds,and three of them are brown. -In which population would it be least likely that an accident would significantly alter the frequency of the brown allele?


A) population A
B) population B
C) population C
D) They are all the same.
E) It is impossible to tell from the information given.

F) A) and B)
G) B) and C)

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No two people are genetically identical,except for identical twins.The main source of genetic variation among human individuals is


A) new mutations that occurred in the preceding generation.
B) genetic drift due to the small size of the population.
C) the reshuffling of alleles in sexual reproduction.
D) geographic variation within the population.
E) environmental effects.

F) C) and D)
G) A) and C)

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The following questions refer to the following paragraph. HIV's genome of RNA includes the code for reverse transcriptase (RT) ,an enzyme that acts early in infection to synthesize a DNA genome from an RNA template.The HIV genome also codes for protease (PR) ,an enzyme that acts later in infection by cutting long viral polyproteins into smaller,functional proteins.Both RT and PR represent potential targets for antiretroviral drugs.Drugs called nucleoside analogues (NA) act against RT,whereas drugs called protease inhibitors (PI) act against PR. -Which of the following represents the treatment option most likely to avoid the production of drug-resistant HIV (assuming no drug interactions or side effects) ?


A) using a series of NAs, one at a time, and changed about once a week
B) using a single PI, but slowly increasing the dosage over the course of a week
C) using high doses of NA and a PI at the same time for a period not to exceed one day
D) using moderate doses of NA and two different PIs at the same time for several months

E) C) and D)
F) A) and B)

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Rank the following one-base-point mutations (from most likely to least likely) with respect to their likelihood of affecting the structure of the corresponding polypeptide: 1) insertion mutation deep within an intron 2) substitution mutation at the third position of an exonic codon 3) substitution mutation at the second position of an exonic codon 4) deletion mutation within the first exon of the gene


A) 1, 2, 3, 4
B) 4, 3, 2, 1
C) 2, 1, 4, 3
D) 3, 1, 4, 2
E) 2, 3, 1, 4

F) D) and E)
G) None of the above

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Use this information to answer the following questions. You are studying three populations of birds.Population A has ten birds,of which one is brown (a recessive trait) and nine are red.Population B has 100 birds,of which ten are brown.Population C has 30 birds,and three of them are brown. -Which population is most likely to be subject to genetic drift?


A) population A
B) population B
C) population C
D) It would depend on the severity of a natural disaster.
E) The population with the higher number of dispersing individuals.

F) A) and B)
G) A) and C)

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Adult male humans generally have deeper voices than do adult female humans,which is the direct result of higher levels of testosterone causing growth of the larynx.If one excludes the involvement of gender in the situation,then the pattern that is apparent in the fossil record is most similar to one that should be expected from


A) pansexual selection.
B) directional selection.
C) disruptive selection.
D) stabilizing selection.
E) asexual selection.

F) B) and C)
G) C) and E)

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Mutation is the only evolutionary mechanism that


A) introduces new alleles into the population.
B) is more important in eukaryotes than in prokaryotes.
C) occurs frequently in all populations.
D) has no effect on genetic variation/evolution.
E) A and C

F) D) and E)
G) A) and B)

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Use this information below to answer the following questions. A large population of laboratory animals has been allowed to breed randomly for a number of generations.After several generations,25% of the animals display a recessive trait (aa) ,the same percentage as at the beginning of the breeding program.The rest of the animals show the dominant phenotype,with heterozygotes indistinguishable from the homozygous dominants. -What is the most reasonable conclusion that can be drawn from the fact that the frequency of the recessive trait (aa) has not changed over time?


A) The population is undergoing genetic drift.
B) The two phenotypes are about equally adaptive under laboratory conditions.
C) The genotype AA is lethal.
D) There has been a high rate of mutation of allele A to allele a.
E) There has been sexual selection favouring allele a.

F) B) and E)
G) A) and B)

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If,on average,46% of the loci in a species' gene pool are heterozygous,then the average homozygosity of the species should be


A) 23%.
B) 46%.
C) 54%.
D) There is not enough information to say.

E) None of the above
F) A) and B)

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Adult male humans generally have deeper voices than do adult female humans,which is the direct result of higher levels of testosterone causing growth of the larynx.If the fossil records of apes and humans alike show a trend toward decreasing larynx size in adult females and increasing larynx size in adult males,then


A) sexual dimorphism was developing over time in these species.
B) intrasexual selection seems to have occurred.
C) stabilizing selection was occurring in these species concerning larynx size.
D) selection was acting more directly upon genotype than upon phenotype.

E) A) and D)
F) A) and C)

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